Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

The kidneys The nephron - Higher tier only Anti-diuretic hormone (ADH) Kidney disease How a dialysis machine works - Higher tier only ...

Drugs with different mechanisms of toxicity frequently affect different parts of the kidney, as is evident from Figure 1, which shows the primary sites of nephron toxicity for various drugs.