Patients with obesity have more orbital fat expansion, which, in the setting of thyroid eye disease, can lead to more severe proptosis, according to research published in BMC Ophthalmology . The study ...
Linsitinib, an oral small molecule under development for the treatment of thyroid eye disease, demonstrated proptosis reduction and safety in the phase 2b/3 LIDS trial, according to a press release ...
Linsitinib is an oral small molecule that inhibits the activity of insulin-like growth factor-1 receptor (IGF-1R). It is believed that inhibition of IGF-1R may help reduce orbital inflammation and ...