Another critical aspect of applying encapsulation to sorting cytokine-secreting cells is the ability to recover the cells in a viable and functionally normal state. Thus, PBMC were encapsulated ...

Siltuximab effectively treated patients who experienced common adverse events after chimeric antigen receptor T-cell therapy, according to findings published in Blood Advances.Results showed the agent ...

1,2 (2) Engineered CAR T cells expressing therapeutic payloads can transform the immunosuppressive environment of solid tumors, such as through producing and secreting proinflammatory cytokines. 3,4 ...

The following is a summary of "Impact of HBsAg reduction via siRNA treatment on natural and vaccine (BRII-179)-induced ...

T cells are white blood cells that ... that Tfr suppresses the production of pro-inflammatory cytokines and alloreactive antibodies from alloreactive B cells to dampen graft rejection ...

The study analyzed both immunological (receptor activation, cytokine secretion, T-cell modulation) and metabolic parameters (metabolic state) in dendritic cells—specific immune cells—derived ...

IN8bio (INAB) unveiled INB-600, its next generation gammadelta T cell-based TCE platform. It is designed to address one of the biggest ...

CAR-T cell therapy is currently used successfully ... it results in lower pro-inflammatory cytokine secretion." Ferreira noted that the team also made sure to run tests on both naive Tregs and ...

In CAR-T cell therapy, clinicians obtain T cell source material directly from a patient (autologous), or from a donor (allogeneic), modify them, and re-introduce them to the patient. Working with ...

Proprietary platform represents the first known approach capable of sustained γδ T cell expansion, eliminating target cells with robust potency; INB-619, a next generation γδ ...