Microglia, the primary immune cells of the central nervous system (CNS), are ... is a hallmark of neurodegenerative diseases. In Alzheimer's disease, microglia initially clear amyloid-β plaques ...
To capture these finer nuances of the movements, the researchers created a biomechanical model based on a neural network ... the early effects of neurodegenerative diseases. More information ...
The transplantation of astrocytes — a type of brain cell as common as neurons — may provide hope of treatments or cures of some neurodegenerative disorders.
Neurodegenerative diseases are characterized by progressive degeneration and loss of neurons, resulting in the deterioration of the nervous system’s structure and function. Multiple sclerosis is ...
Research led by the University of Michigan has provided compelling evidence that could solve a fundamental mystery in the makeup of fibrils that play a role in Alzheimer’s, Parkinson’s and other ...
Neurodegenerative disorders have increasing incidence with limited treatment options. Approaches to target neuroinflammation in various neurodegenerative disorders, such as Alzheimer’s disease (AD), ...
Researchers have long known fibrils—tiny tendrils assembled from invisibly small building blocks called amyloid proteins—are connected to a number of neurodegenerative diseases. But important ...
Tauopathies are neurodegenerative diseases characterised by the build-up in the brain of tau protein 'aggregates' within nerve cells. These include forms of dementia, Pick's disease and ...
Two of the most common neurodegenerative diseases are Parkinson’s (PD) and Alzheimer’s (AD). The growth factors that are responsible for the survival, maintenance, and regeneration of specific ...
Genetic variations in the myeloid immune receptor TREM2 are linked to several neurodegenerative diseases. To determine how TREM2 variants contribute to these diseases, we performed structural and ...