A guardian molecule ensures that liver cells do not lose their identity. The discovery is of great interest for cancer medicine because a change of identity of cells has come into focus as a ...

Scientists at EMBL and DKFZ have discovered how cells in the liver maintain their identity and avoid becoming tumour cells ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or inactivating genes. Precisely fixing disease-causing mutations is far more ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

The liver is a large internal organ that is under your right ribs just beneath your right lung. It has two lobes (sections). The liver is made up mainly of cells called hepatocytes. It also has other ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. The specific functions of these cells in the context of ...

Since symptoms don’t appear until the condition worsens, the only way to detect fatty liver early is through blood tests (LFT ...

Scientists from the University of California Davis have found that ibuprofen, a widely used painkiller, may have a bigger impact on the liver than previously thought. Their research also uncovered ...

This suggests these cells may be useful as new therapeutic targets for various liver conditions. The work appears in the journal Immunity. Macrophages are specialized immune cells located in every ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

Here, we report that TRAIL is constitutively expressed on murine natural killer (NK) cells in the liver and plays a substantial role in suppressing tumor metastasis. Freshly isolated NK cells ...