In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Korro Bio has secured approvals in Australia to commence the Phase I/IIa trial of KRRO-110, aimed at treating AATD.

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

Researchers have developed TRISCO, a cutting-edge microscopy method that enables 3D RNA analysis in whole, intact mouse ...

Mice that had a normal microbiome expressed unique genes in a specific region of the colon compared to germ-free mice. Using single-cell RNA sequencing, the authors found that the changes occurred in ...

Researchers have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the healthy gut and in response to perturbations such as inflammation. They identified ...

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables ...

Our findings show where RNA editing takes place and which factors regulate it, allowing us to understand how RNA editing can ...

A section of mouse intestine with colored fluorescent tags under a microscope. Image: Michael W. Davidson/Florida State University/Zeiss Microscopy At a glance: Scientists mapped gene expression and ...

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of ...

A ground breaking study mapping the immune microenvironment in Multiple Myeloma identifies critical immune changes and ...