Healio9y
Amyloid Cardiomyopathy
[Yancy 2013;15a] Serum amyloid A (AA) amyloidosis (also called secondary amyloidosis), caused by aggregation of the inflammatory protein serum amyloid A. [Yancy 2013;15a; Ash 2020;3a,4d ...
Hosted on MSN1mon
FDA approves Zydus’ Phase IIb trial of Usnoflast for ALS treatment
In addition, the study will analyse biomarkers such as high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-18, IL-6, IL-1β, NLRP3, and serum amyloid A (SAA). Zydus Lifesciences chairma ...
Medical Xpress22d
Peristaltic pump flow: A potential trigger for amyloid protein aggregation
This process involves the formation of amyloid fibrils, crystal-like collections of misfolded proteins that clump together when the proteins are highly concentrated (supersaturated) in liquids ...
Nature3mon
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
Amyloid β protein (Aβ) deposition in the brain is a hallmark of Alzheimer's disease (AD). The fibrillar form of Aβ is neurotoxic, although the mechanism of its toxicity is unknown. We showed th ...