Validation: custom CGH array (NimbleGen) for all reported CNAs Paired normal DNA (skin; 86) 201 acquired CNAs CNAs detected by SNP array but not MC in 40% patients CN-LOH in 8% patients (6 out of ...

Several studies evaluate high-density single-nucleotide polymorphism (SNP) arrays for the detection of copy-number variations in human genomes. Many debilitating diseases have complex genetic ...

A range of technologies can be used in this way, including gene expression profiling, array-based comparative genomic hybridization (aCGH), SNP-CGH and next-generation sequencing (NGS).