This topical JAK inhibitor ointment, developed using CAGE Bio’s proprietary ionic liquid technology, represents a potential breakthrough for low body surface area (BSA), moderate to severe atopic ...

This topical JAK inhibitor ointment, developed using CAGE Bio’s proprietary ionic liquid technology, represents a potential breakthrough for low body surface area (BSA), moderate to severe atopic ...

This topical JAK inhibitor ointment, developed using CAGE Bio's proprietary ionic liquid technology, represents a potential breakthrough for low body surface area (BSA), moderate to severe atopic ...

The gene encodes a ubiquitous non-receptor T-cell protein tyrosine phosphatase that exerts a negative feedback on the JAK-STAT pathway. Limited clinical data is available advocating the use of ...

USA: A recent study has found that in older veterans with type 2 diabetes (T2D), adding sodium-glucose cotransporter 2 (SGLT2) inhibitors to treatment is linked to a higher risk of surgical events ...

Valo Health’s Rho kinase (ROCK) 1 and 2 inhibitor has failed to reduce the severity of diabetic retinopathy in a phase 2 trial, leading the Flagship-founded biotech to drop the candidate.

Additionally, the authors report promising results from a clinical trial with the JAK inhibitor tofacitinib for individuals with dermatological autoimmune disease. Individuals with Down syndrome (DS), ...

1Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2The University of Texas MD Anderson Cancer Center, UTHealth Houston Graduate ...

response to immune checkpoint inhibitors (ICIs), a multicenter study showed. The deep-learning model (called Deep-IO) achieved an area under the receiver operating characteristic curve (AUC ...

Ivarmacitinib, a novel Janus kinase 1 inhibitor, alleviates symptoms, reduces disease activity, and improves physical function and quality of life in patients with moderate to severe rheumatoid ...

Cholinesterase inhibitors prevent the breakdown of a type of neurotransmitter called acetylcholine. Doctors may prescribe this medication for certain neurodegenerative diseases, such as Alzheimer ...