Most antihypertensive drugs target the renin-angiotensin system and fall in two drug classes: angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). ACE cleaves a ...

Drugs for diabetic kidney disease treatment have greatly expanded, allowing research and consensus on their optimal use.

Hypertension (high blood pressure) affects an estimated 1 billion people worldwide and approximately 65 million people in the US alone. If not treated effectively, this common disorder can lead to ...

High blood pressure, also known as hypertension, is a major risk factor for heart disease and comes with a significant ...

If the clinical history is not helpful (e.g., there is no documentation of the efficacy of drug "A"), then measuring a renin level (either plasma renin activity or direct renin) can be helpful ...

Drawing inferences from observational data with possible confounding Heart failure is increasing in prevalence and is a major cause of morbidity and mortality worldwide,1 with prevalence ranging from ...

h Specific for underlying mechanisms (other forms of treatment, including different antihypertensive medications = might ... which suppresses plasma renin activity These disorders should be ...

基于优秀的循证医学证据，2024年，改善全球肾脏病预后组织（KDIGO）发布的CKD临床管理指南推荐SGLT2i作为CKD中的一线治疗药物（图3） [13] ...

"Ultimately, since renin is so critical for our own health ... pressure] and the long-term effects of common blood pressure medications on kidney function and disease." The UVA researchers ...

Drug-resistant infections occur when pathogens change in ways that render antimicrobial drugs ineffective. As a result, the pathogens survive and continue to spread. When infections are treatable with ...

Drugs such as Novo Nordisk’s blockbuster Ozempic can cut drug and alcohol abuse by up to 50% according to a new study, adding to mounting evidence that the drugs yield health benefits beyond ...

Ultimately, since renin is so critical for our own health ... pressure] and the long-term effects of common blood pressure ...