Integration of RNA-seq and AGO2 eCLIP-seq identified miR-1 target genes involved with glycolysis and pyruvate metabolism. The loss of miR-1 in skeletal muscle induced cancer-like metabolic ...
In mammals, pyruvate is the primary substrate for lactate production. It plays a critical role in metabolism by linking glycolysis, where it is produced, with the mitochondrial oxidative ...
What are inherited metabolic disorders? Inherited metabolic disorders — also known as inborn errors of metabolism — are heritable, or genetic, disorders. There are hundreds of known inborn errors of ...