Most-abundant zymogen granule proteins. ‡ Different isoforms present in zymogen granules. § Validated by morphological studies after identification by mass spectrometry. As the molecular ...

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Contemporary thrombolytics in acute ischemic stroke are limited to administration within 4.5 hours of last known normal. JX10 (formerly TMS-007), a Stachybotrys microspora triprenyl phenol family ...

The First Affiliated Hospital & School of Life Sciences, Ministry of Education Key Laboratory for Membrane-Less Organelles & Cellular Dynamics, Hefei National Research Center for Interdisciplinary ...

Two significant threats in this area, neuroviruses and neurocancer, disproportionately affect older demographics. Proteolysis Targeting Chimeras (PROTACs), are groundbreaking molecules that have the ...

These reporters provide a new powerful tool for elucidation of the ubiquitin/proteasome pathway and for high throughput screening of compounds that selectively modify proteolysis in vivo.

David is comprehensively experienced in many facets of financial and legal research and publishing. As an Investopedia fact checker since 2020, he has validated over 1,100 articles on a wide range ...

The ring-like ATPase complexes in the AAA+ family perform diverse cellular functions that require coordination between the conformational transitions of their individual ATPase subunits (Erzberger and ...