Lebanese cannabis oil extract (COE) has been found to provide significant protection against kidney fibrosis caused by folic ...

JNK phosphorylation aids apoptosis via Bcl-2 proteins ... Furthermore, certain target proteins that engage with multiple signaling pathways are pivotal in the prevention and treatment of CI-AKI. Take ...

Mapping the key signaling molecules in biochemical pathways will be central to future ... reactions inside the cell that typically includes phosphorylation of proteins as mediators of downstream ...

The results showed that cordycepin significantly inhibited growth factor signaling in multiple ... through the reduction in the phosphorylation of key pathway components, which also effectively ...

Expression of signal transducer and activator of transcription 1 (STAT1), the mediator of interferon (IFN) signalling, is raised in synovial tissue (ST) from patients with rheumatoid arthritis (RA).

ATR signaling is essential in sensing and responding to the replication stress ... This process is regulated by FOXP1 O-GlcNAcylation, which represses its interaction with ATR, while CHK1-mediated ...

This valuable study investigates the signaling pathways regulating retina regeneration. Solid evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following retinal ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth and tumorigenesis. The evidence supporting the ...

Australia: A recent study published in the New England Journal of Medicine highlighted the potential benefits of oral ...

Reports have shown that PTMs orchestrate OC progression via different mechanisms including the regulation of oncogenic signaling, oncogenic cytokines, autophagy, cell adhesion, metabolic adaption, and ...