A number of putative processes have been implicated including a dysfunction in the descending pain modulatory system in which the periaqueductal gray (PAG) is considered to play a crucial role.

Periaqueductal grey matter (PAG) is a core region of pain processing and modulation networks with possible sex-related implications in migraine. In our study, sex differences of PAG functional resting ...

A recent study led by researchers at the University of Warwick has identified a brain network involved in alcohol addiction.

The intriguing phenomenon of pain suppression was observed by Henry Beecher among soldiers during WWII. Pain, often deemed an ...

Fundamental concept to first understand is that you don’t detect pain – it is a sensation that your brain has created – from ...

"They just need to change their mindset,” some leaders say. Mindset is powerful and malleable. But we can have greater impact ...

In the second world war, the physician Henry Beecher observed that some of his soldier patients, despite being injured on the ...

It works by switching off nociceptors in the peripheral nervous system, and therefore preventing pain signals getting to the ...

Animals rely on instinctive behaviors to respond quickly to threats and opportunities. These automatic reactions, crucial for ...

Researcher suggest findings could help understand what happens in the brain when fear response regulation is impaired.