【导读】胰腺癌肝转移是导致预后不良的一个重要因素。肝转移中适应性免疫重塑的细节，尤其是中性粒细胞的作用，仍然难以捉摸。在这项研究中，单细胞测序与空间转录组学相结合的结果显示，与原发肿瘤相比，肝转移瘤表现出更具侵袭性的转录特征和更高水平的免疫抑制。20 ...

A research paper published in Nature Cancer details new insights into the role of efferocytosis—the burying of dead cells—in pancreatic cancer that spreads to the liver. Liver metastasis ...

The pORG gene set comprises a total of 55 genes that were overexpressed in liver-metastatic primary tumors. As compared to pancreatic cancer subtype classifier (PurIST), which is a PDAC ...

Pancreatic cancer is generally characterized by a poor prognosis. Patients with lung-metastatic pancreatic ductal adenocarcinoma survive longer than those with liver metastases. A study now ...

For example, if cancer of the pancreas spreads to the liver, the cancer cells in the liver are pancreatic cancer cells. The disease is metastatic pancreatic cancer, not liver cancer. It is treated as ...

By Dr. Sanchari Sinha Dutta, Ph.D. New research uncovers how distinct molecular profiles and immune signatures in metastatic ...

More information: Bharti Garg et al, MICAL2 Promotes Pancreatic Cancer Growth and Metastasis, Cancer Research (2025). DOI: 10.1158/0008-5472.CAN-24-0744 ...

Pancreatic cancer kills 50,000 people each year, according to the National Cancer Institute and there are few effective treatment options for the disease. In a new study, researchers at the University ...

The American Cancer Society's annual cancer trend report shows cancer mortality is decreasing but cancer rates are increasing in young adults and women.