Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the ...

Request To Download Free Sample of This Strategic Report @ Highlighted with 78 tables and 119 figures, this 215-page report ?Global Biopharmaceuticals Market 2023-2033 by Product Type, Testing ...

Role of Mutant p53 Contributes to Autophagy Regulation in Cancer FIGURE 2. Biological function and molecular mechanism of autophagy pathway. Autophagy has been initiated by the formation of ...

Background While p53 mutations occur early in Barrett’s oesophagus (BE) progression to oesophageal adenocarcinoma (EAC), their role in gastric cardia stem cells remains unclear. Objective This study ...

When you first enter a new world, you can either spawn near a structure or find one while exploring any of the three dimensions. While finding some can be quite easy, others are extremely hard to ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

For each ligand, the following information is provided: PDB ID, molecular weight (MW), the computed sum of possible hydrogen bond acceptors and donor groups (a_accdon, descriptor from MOE2022), log ...

p53 dysfunction and mTOR pathway hyperactivation are hallmarks of human cancer ... In mammalian cells, mTOR forms two complexes with distinctive structure and functions, namely mTORC1 and mTORC2.