Nanoscopic DNA chips assembled using the DNA origami method enable target detection in solution and hold promise for single-cell gene expression analysis. In 2006 Paul Rothemund of the California ...

The paper says the new strategy is scalable and cost-effective, as it works with existing origami structures, does not ...

The sensor uses a DNA origami scaffold, which consists of two arms connected by a molecular “hinge.” Each arm is tagged with a fluorescent dye, and the distance between the tags is recorded by means ...