Members of the nuclear receptor superfamily of transcription factors have important roles in modulating the responses of macrophages, microglia and lymphocytes to pro-inflammatory signalling ...

The superfamily of nuclear receptors can accommodate both relatively rigid ligands as well as conformationally flexible ligands. Examples of the influence of ligand shape and flexibility on the ...

Donald Patrick McDonnell, Ph.D., has been awarded the Endocrine Society’s John D. Baxter Prize for Entrepreneurship for discovering hormone therapies for treating breast and prostate cancer, the ...

Work at the University of Florida has led to the identification of nuclear receptor subfamily 1 group D member 1 (Rev-erbA-α) antagonists reported to be useful for the treatment of cancer, sarcopenia ...

China National Nuclear Corporation’s (CNNC ... Lu-177 is particularly important in peptide receptor radionuclide therapy (PRRT). Since it releases low-energy beta particles that can penetrate ...

Olema is advancing a pipeline of novel therapies by leveraging our deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Our lead product candidate, ...

Live webcasts of these presentations will be available in the Events and Presentations section of Olema’s investor relations website at ir.olema.com. The webcasts will be archived for at least 30 days ...