The sequence homology across the nuclear receptor superfamily indicates that these receptors evolved through divergent evolution 5, but gives no information about the role of ligands in the ...
The classic estrogen receptor signaling pathway occurs through the entry of estrogen into the cell, translocation to the nucleus, interaction with the nuclear estrogen receptor (ER) α or β ...
"It binds to and activates the PPAR δ nuclear receptor. When you turn it on, it promotes cancer. It can stimulate cell proliferation and affect inflammatory pathways," DuBois said. "We found that ...