Sholler has performed animal experiments 1 confirming that DFMO can effectively block tumour formation in mice transplanted with neuroblastoma cancer stem cells. Sholler’s past work garnered ...

Childhood neuroblastoma is often a fatal disease ... enhancing irinotecan’s ability to penetrate cancer cells. It also disrupts the tumor’s ability to repair DNA damage caused by chemotherapy ...

Neuroblastoma is a rare solid tumor that develops in immature nerve cells. This type of cancer primarily affects children five years of age and younger and is associated with high relapse rates.