Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

The Apennine brown bear, also known as the Marsican brown bear (Ursus arctos marsicanus), is a unique and critically ...

Given that the role of PRMT1 in metabolic regulation has been well-documented, we then investigated whether PRMT1 is involved in transforming 6133 cells through metabolic reprogramming. To assess this ...

Scientists found a genetic mutation in Italy’s Apennine brown bears that reduces energy production and increases harmful ...

Peptides have emerged as a fascinating class of biomolecules with multifaceted roles across biological systems. Vesugen, a ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

A new study reports that later-onset menopause is associated with a reduced risk of cardiovascular compared to those who stop ...

The study shows that mitochondria do more than provide energy; they play an active role in modulating the immune response.

With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which ...

A study published in Scientific Reports found that cannabidiol (CBD) disrupts lipid metabolism and induces apoptosis in ...

InFlectis BioScience SAS, a drug discovery company pioneering development of therapeutics harnessing the Integrated Stress ...