Department of Health Industry Technology Management, Chung Shan Medical University, Taichung 40201, Taiwan Department of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, ...

Since NRF2 defends against oxidative stress by switching on a suite of protective genes, GSK3β hamstrings neurons’ ability to survive. “Kampmann’s team demonstrated that unbiased CRISPRi screening ...

Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

Gao et al. (158) developed the (Q@CeBG nanoreactor, which combines CeO 2 nanozyme and quercetin) and has shown potential in reducing OS and polarizing microglia from a pro-inflammatory to an ...

Human breast cancer cell lines-derived xenograft tumor explants assay was used to evaluate the compound’s efficacy and to assess the induction of methuosis via NRF2 activation by tanshinlactone.