Adverse drug reactions (ADRs) remain a common clinical problem since they can mimic many diseases and cause significant morbidity and mortality. Judicious prescribing is important to minimize ...

A lichenoid drug reaction should be suspected if the eruption is photodistributed and widespread. Additionally, lichen planus has recently been associated with hepatitis C and all patients ...

Biopsy confirmed a lichenoid drug eruption. The medication was discontinued and she was treated with topical steroids and a calcineurin inhibitor, with resolution of her lesions. Clinicians should be ...

The results of the RELIEVE UCCD study in patients with moderate-to-severe ulcerative colitis (UC) and Crohn's disease suggest a "best-in-class potential" for the drug, which Sanofi licensed from ...

The ability to stratify mortality and performance characteristics (sensitivity, specificity, positive predictive value, negative predictive value and area under the receiver operating curve) were ...

Drug safety relates to the potential for adverse effects related to the administration of drugs. Efforts to establish the safely profile of drugs begin early in their development, with in vitro ...

Vanda Pharmaceuticals Inc. failed to convince a federal judge that the FDA unlawfully approved a generic version of its drug used to treat non-24-hour sleep-wake disorder. Judge Tanya S. Chutkan of ...

nwhcn.org.au) Objective—To determine whether minimum clinically significant difference in visual analogue scale (VAS) pain score varies according to the severity of pain reported. Method—Prospective ...

“Patients with [substance use disorder] often use drugs that significantly influence pupillary reactions,” the study authors explain. “Despite their widespread use, smartphones have not been widely ...

This project focuses on computational drug discovery for Hypertrophic Cardiomyopathy (HCM) using machine learning techniques. The primary target is TNNI3, a gene linked to HCM. The study leverages ...

This project has not set up a SECURITY.md file yet.