近日，来自复旦大学附属中山医院血液科的研究人员在《Cell Death and Disease》期刊上发表了题为 “Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway” ...

These biological responses to AZD1480 are associated with concomitant inhibition of phosphorylation of JAK2, STAT3 and MAPK signaling proteins. In addition, there is inhibition of expression of ...

INTRODUCTION: To identify changes in interleukin (IL)-6 levels and its pathway (Jak/stat3) in the human placenta during preterm and term labor, placental tissues were collected from primiparous ...

A recent study published by the lab in Nature Communications [2024; PMID: 38355560] sheds light on this aspect by elucidating the role of the IL6/JAK/STAT3 signaling pathway in driving bladder cancer ...

Immune cells process such signals through the JAK-STAT signaling pathway—named after Janus, the two-faced Roman god of beginnings and endings. This pathway links signal detection on the cell ...