Using ALK+ lung cancer patient-derived cell lines, researchers have performed phosphoproteomic screening and identified guanylate kinase 1 (GUK1) as a TKI sensitive metabolic molecule in ALK-driven ...

ALK’s (ALKB:DC / OMX: ALK B / AKBLF) Board of Directors has approved the 2024 annual report. Following a robust performance in Q4, full-year results were in line with the latest outlook and represent ...

In this article, we are going to take a look at where Alaska Air Group, Inc. (NYSE:ALK) stands against the other transportation stocks. Trump’s tariffs threat is making the broader market more ...

A new FDA approval stands to give Daiichi Sankyo’s Turalio some company in a rare tumor type. Fellow Japanese drugmaker Ono Pharmaceutical has won an FDA green light for vimseltinib to treat ...

H. Ma and S. Srivastava are joint first authors of this article. R. Sundar and P. Tan are joint corresponding and senior authors of this article.

Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia ...

Working with mouse models and human cancer cells, the researchers identified a metabolic enzyme called GUK1 in lung cancers harboring an alteration in the ALK gene. Their experiments showed that ...

IL-36 receptor is crucial for host defense and tissue repair. Here, the authors describe identification and characterization of low molecular weight inhibitors of the IL-36 receptor using encoded ...

is the most common type of lung cancer. It’s rare, but some people have NSCLC with “ALK rearrangement” or “ALK mutation.” You might also hear your doctor call this type of cancer ALK ...

1Division of Cancer Genome Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), and National Center for Tumor Diseases (NCT), Heidelberg, Germany 2German Center for Lung ...

Pathologic diagnosis for this patient revealed that the morphology of “right upper lung mass” was considered as inflammatory myofibroblastic tumor with endovascular changes. Immunohistochemical ...