In summary, IRF2BP2 expression in macrophages/microglia is important to limit inflammation and stroke injury, in part by mediating the beneficial effect of IFNβ. Ischemic stroke occurs from an abrupt ...

We welcome contributions addressing various themes within this scope, including but not limited to: · Molecular and cellular mechanisms underlying hypoxic/ischemic brain injury. · Automated analysis ...

Hypoxia-ischemia induces an inflammatory response in the immature central nervous system that may be important for development of brain injury ... a chronic state of inflammation (Fig.

Because both inflammation and hypoxia-ischemia have the ability to contribute ... We extend the possibility of UPR-induced apoptosis to the brain of the most vulnerable humans, those born much ...

Background: Brain inflammation following ischemic stroke exacerbates neuronal injury. Early immune cell infiltration into the brain after ischemia is correlated with increased risk of subsequent ...

"Smokers face an elevated risk of developing an array of cardiovascular diseases, and many require advanced interventional ...

Comparing with the mice treated with NS, P-selectin in the ischemic brain tissue were significantly decreased after injected with GSNO ... 62%, p =0.69）than NS (Fig2). Conclusions: GSNO reduced ...

Flossing your teeth at least once a week may do more than protect against cavities. A new study suggests it could lower the ...

These findings are valuable because they shed light on the function of astrocytes from the adult SVZ in pathological states like brain ischemic injury. The results are convincing, as they rely on a ...

While flossing is one possible way to reduce stroke risk, experts still recommend other key steps for a healthy heart and ...

These findings are valuable, despite being mostly descriptive, as they point to a relevant function of SVZ newborn astrocytes in the modulation of the glial scar after brain ischemia. The methods, ...