A team of researchers led by Professor Ningling Kang, PhD, at The Hormel Institute, University of Minnesota, has published an ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The paradigm of stellate cell activation provides an important ... The most effective way to eliminate hepatic fibrosis is to clear the primary cause of liver disease. The latter includes ...

Carisma Therapeutics Inc. (CARM) presented promising preclinical data on engineered macrophages for treating liver fibrosis at the ...

Learn about HMGB1's crucial role in liver diseases, its pathways and therapeutic potential that can treat liver diseases.

It was also revealed that the terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and CD68-double-positive apoptotic KCs located in the portal or fibrotic septa area were situated ...

The first coating uses the membranes of hepatic stellate cells, which are key to the liver’s response to injuries. When activated, these membranes express a receptor that homes in on and binds ...

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be ...

The two other genes, MAT2A and MAT2B, are active within a second kind of liver cell called stellate cells, which also play a role in fibrosis. All three genes "code" for different proteins necessary ...

Objective Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease ...

The two other genes, MAT2A and MAT2B, are active within a second kind of liver cell called stellate cells, which also play a ...