In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

A gene variant present in most people might have contributed to cognitive differences between humans and their closest ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Like a movie editor removing bloopers, our cells also edit their protein machines to make films worth watching. New research ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

The FDA on Wednesday approved the industry’s first-ever tablet treatment for spinal muscular atrophy— Roche ’s SMN2 splicing ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...