Fibroblasts, cells that produce and organize the extracellular matrix (ECM) appear to be in cahoots with metastasizing tumor cells, according to research presented at the annual meeting of the ...

Researchers from Osaka University find that a protein subunit, AP2A1, might be partly responsible for the peculiar structural ...

Intercellular communication between tumor cells and cancer-associated fibroblasts (CAFs) plays a key role in tumorigenesis ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

As noted in the abstract of this paper, dermal fibroblasts orchestrate the synthesis and degradation of extracellular matrix components, which is crucial for skin homeostasis. Alterations in the ...

Specialised fibroblasts, tenocytes, lie within these fascicles and exhibit high structural ... This specialised arrangement is related to their function, as tenocytes synthesise both fibrillar and non ...

A collaborative research team from POSTECH has successfully developed a gastric cancer model using 3D bioprinting technology ...

Cancer models developed with 3D bioprinting technology allow for rapid evaluation of individual drug responses.

Fibroblasts are specialized cells in connective tissues that play an important role in wound healing and tissue repair. They produce and organize the so-called extracellular matrix, a network of ...

Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of actual ...