However, the biopsy procedure itself and the need to expand fibroblasts in culture still represent major hurdles to be overcome before the iPS cell technology can become more broadly applicable.

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

Our research focuses on the tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function as well as immune ... three-dimensional cell culture systems such as patient-derived ...