Limited (“HUTCHMED”) (Nasdaq/AIM:HCM; HKEX:13) today announces that it will receive a US$10 million milestone payment by its partner Takeda (TSE:4502/NYSE:TAK). Takeda received a national ...

Researchers discovered a vulnerability in viral enzymes that could lead to novel treatments for diseases as diverse as COVID-19 and Ebola -- while also minimizing side effects and reducing the odds of ...

The arrival of Paxlovid in December 2021 marked another turning point in the COVID-19 pandemic-;an effective antiviral that has since successfully treated millions.

Researchers have introduced a proof-of-concept for a new class of antivirals that could be used against RNA viruses including ...

Drug (purple) that inhibits viral mRNA cap methyltransferase NSP14 for antiviral therapy. Drug binding requires the presence ...

The current study presents useful findings about the inhibition of a membrane pyrophosphatase by non-hydrolyzable phosphonate substrate analogs. The study proposes a model in which the two monomers in ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

Inflammation is limited when the enzyme signaling pathways are interrupted, which can help some autoimmune diseases. In this article, learn about the dosage, uses, and ongoing research underway for ...

Corydoras like to root around in the substrate for food. So what should we use in the aquarium to allow them to behave naturally, without damage to their barbels? Heiko Bleher explains. I strongly ...

Enzymes are present in microorganisms, plants and animals and act as catalysts in various chemical reactions. This means that they increase the rate of the reactions. Because of this they can be ...

Washing dusty gravel or sand is messy, tedious and, in winter, rather cold work. The best way to get the substrate clean is to place a small quantity (say a few mugfuls) in a clean bucket and spray ...

The reaction system is of great complexity that involves multiple macro- and micro-factors of substrate properties, diverse enzymes and intervention from other proteins ... It was because the gas flow ...