Splicing accuracy enhanced This process is crucial for the life of the cell. "The spliceosome is composed of multiple components that secure production of functional proteins controlling cellular life ...

Genes contain the essential building instructions for life, guiding cells on which amino acids to assemble in what sequence to produce specific proteins. The human genome codes for about 20,000 such ...

Cells adjust the expansion and networking of their internal canal system as needed. A process known as ER-phagy (“ER-eating") ...

Cells adjust the expansion and networking of their internal canal system as needed. A process known as ER-phagy ("ER-eating") plays a central role here. During this process, a part of the membrane of ...

Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed—for instance in case ...

The ER-phagy receptor FAM134B is initially distributed via the membrane surface (left). Its IDRs move back and forth in a largely disordered manner, like tentacles. The formation of local clusters ...

remodelling across neuronal subcompartments and decode the substrate selectivity of ER-phagy receptors during in vitro neurogenesis. Single-cell multi-omics of arrested human embryos reveal that ...

When patients use non-ER facilities, it's less costly for the insurer, and that translates into lower overall healthcare costs—and lower insurance premiums—for everyone. But in the case of a life- or ...

Actress-turned-politician Girlie “Maita” Javier-Ejercito died at the age of 55 on November 3, 2024. Former Laguna Governor and action star ER Ejercito announced heartbreaking news early Sunday morning ...