Six normal human volunteers as renal transplant donors were given 3 H-digoxin before and again after unilateral nephrectomy. The serum digoxin concentration was modestly increased following ...

The administration of i.v. argatroban did not affect the steady-state pharmacokinetics of oral digoxin after 15 days of therapy. Because subjects with normal renal function primarily eliminate ...

Discover the supplements pharmacists say they wouldn't take and why they could be harmful to your health. Get tips on how to buy and take supplements safely.

A strong argument can be made that the most appropriate therapy for heart failure in the African-American patient is a regimen of ACE inhibitors plus β-blockers with diuretics and digoxin as ...

Only the best Keurig machine can extract the maximum flavor from your K-Cups. We gathered 11 of the top-selling Keurig coffee makers and brewed the same pods in all of them to determine which ...

Tumor necrosis factor (TNF) is a pleiotropic cytokine belonging to a family of trimeric proteins with both proinflammatory and immunoregulatory functions. TNF is a key mediator in autoimmune diseases ...

The results of the FRAIL-AF trial3 are highlighted, showing that in a population of AF patients aged ≥ 75 years with frailty, polypharmacy, and a stable international normalized ratio with good time ...

Pharmacokinetics is an area of pharmacology concerned with the time course of absorption, distribution, metabolism and excretion (collectively ADME) of drugs from biological systems in order to ...

Rigel Pharmaceuticals, Inc.  today announced the first patient has been enrolled in a Phase 1 study evaluating the safety and tolerability of escalating doses of fostamatinib, the company's oral ...