Dendritic cell subtypes work in concert to activate ... Immunicum is also advancing the development of DCP-001 as a cell-based relapse vaccine. Because DCP-001 cells are derived from a cancer ...

Dendritic cells are poised to revolutionize oncology. This type of immune therapy shows effectiveness even in late-stage ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

Dendritic cells (DCs) actively participate in maintaining ... tolerogenic and immunogenic functions of DCs and instigate the development of autoimmune diseases. This article provides an overview ...

Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role ... and ...

We are investigating the molecular biology of Coxsackie B virus infection in three human beta cell lines and human white blood cells, particularly plasmacytoid dendritic cells. Our hypothesis is that ...

Dendritic cells—the immune system's best antigen ... This technology holds promise for tackling a range of diseases where ...

"Her entrepreneurial background, clinical development expertise and physician-patient experience will be essential in ...