Researchers have identified genetic variations in brain cells, particularly microglia and oligodendrocytes, that influence ...

This review provides an overview of Alzheimer’s disease (AD), discussing its complex pathophysiology, risk factors, and ...

Alzheimer’s disease is the most common form of neurodegenerative disease, estimated to contribute to 60–70% of all cases of dementia worldwide. Increasing evidence suggests that neuroinflammation, ...

Thus, Pin1 is a vital protein involved in the pathogenesis of both cancers and Alzheimer's dementia. While overexpression of Pin1 is associated with various oncogenic pathways, depletion of Pin1 ...

and added additional support for the involvement of vascular mechanisms in dementia pathogenesis." The study concluded that ...