Some DNA damage evades repair for years, causing repeated mutations during cell division, increasing cancer risk, especially ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

The epithelial cells that line our surfaces ... undergo relatively constant turnover to replace the damaged cells. To do so, epithelia set aside reservoirs of proliferative progenitor cells ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

The healing of an epithelial defect requires epithelial cell migration, adhesion and mitosis. The epithelial cells must migrate over the epithelial defect. This step requires healthy limbal stem ...

Cell competition in epithelial tissue eliminates transformed cells expressing activated oncoproteins to maintain epithelial homeostasis. Although the process is now understood to be of mechanochemical ...

Bowel cancer begins in the epithelial cells which line the bowel and these T cells patrol this area attacking any threats, such as damaged cells or small tumours, before they cause harm.

Inhibiting the HIF2 protein was found to promote repair processes in a mouse model of lung injury, and may be a strategy for ...