Electroretinograms, however, are usually not detectable in Leber congenital amaurosis, and signals from a small region treated with gene therapy might be lost in noise. For this study, 7 investigators ...

Scientists have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect. Scientists at the Icahn School of Medicine at Mount Sinai and ...

The onset, progression and cause of the corneal opacity should be investigated to determine potential for visual improvement. Preoperative evaluation should include assessment of the current level ...

What Is a Corneal Ulcer? A corneal ulcer is an open sore on your cornea. That's the thin, clear layer over your iris (the colored part of the eye). It’s also known as keratitis. People who ...

However, babies and children can be born with cataracts, or they may develop them as they age. A congenital cataract causes the same symptoms as adult cataracts—a clouding in the lens of the eye that ...

With significant advancement in medical science and surgical techniques, corneal transplant surgeries are now increasingly effective at restoring vision in patients with corneal diseases. In the last ...

The following is a summary of “Corneal Opacity in the United States: An American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) Study,” published in the January 2025 issue of ...

At present, there are about 4 million patients with blindness caused by keratopathy in China, and more than 100,000 new cases are added each year (1). Corneal transplantation is the most effective ...

Moreover, treatment with GLY reduced the degree of cornea opacity through inactivating extracellular HMGB1 function, which otherwise induces TGF-β1 release and myofibroblast differentiation.