Background PARP inhibitors (PARPi) have been licensed for the maintenance therapy of patients with metastatic pancreatic cancer carrying pathogenic germline BRCA1/2 mutations ... Mechanisms were ...

Following neonatal H-I brain injury in mice (a model of cerebral palsy), there was evidence of apoptotic changes (neuronal caspase-3 activation), as well as accumulation of clusterin in dying neurons.

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

Correspondence to Dr Florencia McAllister, Department of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; fmcallister{at}mdanderson.org In summary, ...

As we wait for new episodes, we're compiling everything we know about Ginny & Georgia Season 3, including scoop from Howey and Gentry on what we can expect next. Netflix finally announced a ...

Cayman Islands, January 28, 2025 – Silexion Therapeutics Corp. (NASDAQ: SLXN) (“Silexion” or the “Company”), a clinical-stage biotechnology company pioneering RNA interference (RNAi ...

Pamrevlumab plus nab-paclitaxel/gemcitabine (Pam + GA) as first- and second-line therapy in metastatic pancreatic cancer (mPDAC): Results from Precision Promise (PrP ...

Using the recombinant baculovirus BacCMV-GFP, enhanced GFP (EGFP) expression was observed in both primary mouse and human pancreatic dissociated islet cells (Figs. 2 and 3) at a multiplicity of ...

While researchers haven’t yet established a direct link between Red 3 and cancer in people, substantial evidence from animal studies points to its carcinogenic potential. California’s 2023 ban ...

Type 1 diabetes mellitus (T1DM), known as insulin-dependent diabetes mellitus, is characterized by persistent hyperglycemia resulting from damage to the pancreatic β cells and an absolute deficiency ...