By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...

enzyme background stock illustrations Gold pill capsule or gold drop with vitamin C Gold pill capsule or gold drop with vitamin C on a transparent background. Medical or medical template. DNA 3D ...

Danielle is an Assistant Editor at The Scientist. She has a background in neuroscience and molecular psychiatry. She has previously written for BioTechniques News, The Scientist, and Drug Discovery ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Scientists from Australia have successfully bioengineered genetically modified fruit flies and zebrafish capable of absorbing ...

Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk ...

A CRISPR-based system that erases itself from fly populations may offer a safer approach to tackling insecticide resistance while minimizing ecological risks.

为解决 ADHD 现有治疗手段的局限，3Z 等单位的研究人员开展氨氯地平作为新型 ADHD 治疗药物的研究。结果发现其能改善动物 ADHD 相关行为，且在人类遗传数据中也有疗效。推荐阅读，助力探索 ADHD 治疗新方向。

纤维素作为地球上最丰富的可再生聚合物，其生物解聚过程面临诸多挑战。尽管它由葡萄糖残基构成，但结晶微纤维结构以及与木质素、半纤维素在植物细胞壁中的紧密结合，使得纤维素对降解具有高度抗性，自然分解过程缓慢，且依赖复杂的多组分酶系统。