Skeletal muscle tissue demonstrates global hypermethylation with aging. However, methylome changes across the time-course of ...

Researchers find that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, driving neuroinflammation, ...

H3 demethylation that modulates MKP-1/MAPK signaling may account for the long ... cells undergo transient changes in intracellular calcium and that depolarization of these cells induces BMP4 ...

Calcium lactate is calcium paired with lactic acid. The body needs calcium to support bone, heart, muscle, and nerve health. Boosting calcium intake through supplements or food may help reduce cancer ...

Calciphylaxis is a kidney complication causing calcium buildup inside fat and skin blood vessels. It leads to painful skin lesions and often causes serious infection. Clinical trials are ...

Calcium is an important mineral that our bodies need to keep us healthy. Having cancer can affect the amount of calcium in the body. High blood calcium levels sometimes happen if your cancer is ...

Stress granules (SGs) form in response to diverse environmental signals. Here, the signaling pathways that connect lysosomal stress to SG formation are characterized. A calcium-dependent pathway ...

Furthermore, Sat1 and its interacting genes were enriched in several signaling pathways, including ferroptosis and the MAPK signaling pathway. The results showed that Sat1 regulated MIRI through ...

These findings further demonstrate that secondary metabolites, as signaling molecules, play a crucial role not only in ... Kinases (MAPKKKs), triggering a series of defense responses, such as ROS ...

Fas signaling may also be involved in T cell costimulation and proliferation. Although Fas deficiency in humans and mice predisposes them towards systemic autoimmunity, Fas-FasL interactions can ...

we developed a computational model of five signaling pathways (including two novel pathways) leading to ERK activation during L-LTP induction. We show that calcium and cAMP work synergistically to ...