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This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...

Request permissions for this article. From the Saha Cardiovascular Research Center (C.W., A.D., H.S.L.), University of Kentucky, Lexington. Department of Physiology ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Expression of the receptor RAGE in biliary ...

The assertion that the heart contains its own dedicated cardiomyocyte-producing stem cell is absolutely central to the entire cardiac regeneration–stem cell debate. If the heart truly lacks such an ...

Cell competition in epithelial tissue eliminates transformed cells expressing activated oncoproteins to maintain epithelial homeostasis. Although the process is now understood to be of mechanochemical ...

23 Cre was activated by intraperitoneal injections of tamoxifen at a dose of 1 mg/d for 5 subsequent days at the age of 4 weeks. Control animals were treated with corn oil, the solvent of tamoxifen.