In a study of identical twins, a team led by PD Dr. Lisa Ann Gerdes (Institute of Clinical Neuroimmunology at LMU University ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

A study involving identical twins suggests alterations in immune cells called CD8 T-cells may be early drivers of ...

Metabolic factors influence tissue immunity in an intricate interplay between nutrient availability, organelle biology and tissue-resident memory T (TRM) cell development.

Discover research by Hongbo Chi, PhD, that uncovers the interplay between organelles, nutrient-dependent signaling pathways ...

A cancer vaccine that had little success in clinical trials for patients with advanced tumors could potentially have efficacy ...

26 in Nature Immunology, the researchers discovered that activating a metabolic pathway called the pentose phosphate pathway makes antitumor CD8 T cells more likely to stay in an immature ...

Immatics, a biotech company working on promising cell-based immunotherapies for solid cancers, has a promising TCR-engineered ...

CAR-T cell products’ quality control standards incorporate characterization, uniformity, and purity testing to ensure and ...

The treatment also activated patients’ immune systems, with effector CD8+ and CD4+ T cells successfully infiltrating tumors, ...

*仅供医学专业人士阅读参考把肿瘤微环境内因抗原慢性刺激转入耗竭状态的CD8+T细胞“叫醒”，让它们重新活化为效应CD8+T细胞，是PD-1/L1抑制剂为代表的现有免疫治疗起效的关键，但实话实说，激活处在耗竭状态的CD8+T细胞，在奇点糕眼里总觉得有点 ...