A second south coast club visits Old Trafford inside a week as Ruben Amorim looks to record back-to-back Premier League wins for the first time as manager after scrapping past Southampton in midweek.
Darwin Nunez struck twice in stoppage time to earn Liverpool a 2-0 win at Brentford and a six-point Premier League lead over Arsenal, who blew a two-goal lead to draw 2-2 against Aston Villa.