However, the terminal half-life of amphotericin B deoxycholate after accumulation is prolonged (up to 15 days); since the drug is excreted very slowly (over weeks to months) by the kidneys ...

Renal dysfunction while receiving amphotericin B deoxycholate was defined as an increase in the SCr concentration to above 2.5 mg/dL. By the end of therapy with amphotericin B colloidal dispersion ...