Reproduced with permission from [1]. Endothelin-1 Causes vasoconstriction of both afferent and efferent arterioles, leading to decreased renal blood flow and glomerular filtration rate [127,128] ...

• Fenoldopam (a medicine that rapidly widens and relaxes blood vessels) probably reduces the risk of developing acute kidney injury (AKI) (a condition where the kidneys suddenly lose their ability to ...

ATP hydrolysis releases free adenosine into the extracellular space, which in turn acts on adenosine A1 receptors in the afferent arterioles and causes local constriction, thereby reducing RBF and ...

Alternatively, these body temperature effects may originate from the modulation of TRPV1 on vascular smooth muscle cells (vSMCs), where channel activation promotes arteriole constriction. Here, we ask ...

Despite decades of research, we lack a mechanistic framework capable of predicting how movement-related signals are transformed into the diversity of muscle spindle afferent firing patterns observed ...