The purine/purinergic system has emerged as a fundamental regulator of cellular communication, influencing various physiological processes such as metabolism, energy balance, and signal transduction.

H 2 S generated by adipose tissues regulates the local insulin sensitivity. H 2 S can act as an 'adipocytes-derived relaxing factor' in aortic periadventitial adipose tissues. H 2 S plays ...

Hesperetin activated the adipose thermogenic program and facilitated metabolic homeostasis in mice with diet-induced obesity (DIO) dependent on ADGRA3. In the present study, we have elucidated a novel ...

Strategy to investigate the role of ADGRA3 in WAT beiging: Having identified ADGRA3 as their candidate receptor, the authors investigated the receptor in mouse models, the murine inguinal adipocyte ...

Members of the Proud Boys, key instigators in the Jan. 6, 2021, Capitol riot, are mobilizing in support of Donald Trump—and in some cases, making threats about the presidential election. While ...

Adipose tissue is an active immune and endocrine organ, whose adiposopathic obesity-mediated dysfunction contributes to metabolic abnormalities often encountered in clinical practice, including ...

A TV screen reports North Korea's intercontinental ballistic missile launch during a news program at the Seoul Railway Station in Seoul, South Korea, Thursday, Oct. 31, 2024. (AP Photo/Lee Jin-man ...

Then there’s the question of virtue signalling. This is a phenomenon where consumers purchase highly visible green products primarily to signal they’re a person who cares about the environment ...

A class of chemicals –– likely in products all over many homes in the United States –– could be impacting your hormone health. The scientific literature around EDCs is still growing, but ...