In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.
Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, ...
“Researchers looked at a protein in the brain called ‘S-acyltransferase’, which has been linked to cognitive decline in Alzheimer’s disease. By targeting this protein with a nasal spray they found ...
How? By targeting a specific enzyme in the digestive system, SOAT2. This enzyme, sterol O-acyltransferase 2 (SOAT2), regulates fat absorption by facilitating its incorporation into the cells of the ...