Mechanisms that have been characterized in SSc include DNA methylation and histone acetylation and deacetylation. Both DNA methyltransferase inhibitors and HDAC inhibitors have been successfully ...

Epigenetic modifications, such as histone acetylation and methylation, influence the consolidation and retrieval of fear memories, providing potential therapeutic targets for memory modification.

Our results suggest that HDAC6 inhibits cGAS activation through TRIM56 deacetylation in a species-specific manner. TRIM56 K110 acetylation promotes cGAS monoubiquitination and its DNA binding ability.

By modulating the interaction of glycoproteins with galectins and other lectins, O-acetylation influences how these glycoproteins cluster and move within the plasma membrane to allow for longer ...

2013). Some natural and semisynthetic quercetin derivatives exhibit improved biological activities compared to quercetin (Dok-Go et al., 2003). Acetylation of the hydroxyl groups in quercetin has been ...

The new year brought a few new laws to the D.C. area. Although July 1 and Oct. 1 are generally the big dates for new laws going into effect, here are a few you'll want to know about, whether you ...

The Young and the Restless spoilers reveal there is no new episode on Wednesday, January 1. So, what’s happening on Thursday, January 2, 2025? Fans will see Mariah Copeland (Camryn Grimes) react to ...

Soweto-born dancer and choreographer Dada Masilo has died. A statement shared by her management revealed she died aged 39 on December 29 after a “brief illness”. “The Masilo family have ...

“I went from thinking everything was going to be fine to more than likely I'll be dead in the next five years," says Joshua Ray Walker of his up-and-down cancer battle in 2024. He's photographed ...

In this useful study, the authors show that N-acetylation of synuclein increases clustering of synaptic vesicles in vitro and that this effect is mediated by enhanced interaction with ...

The Trump family Christmas card is making its way onto social media as grateful MAGA recipients are gleefully sharing images of the holiday greeting. The bright red card features a gold star with ...