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上海交大商明课题组JACS:首例配体驱动的铜催化核苷类ProTide前药的 ...
近日,上海交通大学变革性分子前沿中心的商明课题组实现了首例配体驱动的廉价金属铜催化核苷类ProTide前药的不对称合成,相关研究成果在Journal of the American Chemical Society上发表。 正文 核苷类药物在抗病毒、抗肿瘤药物中占有相当比重,其在酶催化下可 ...
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