Here we show that KIF12 kinesin suppresses MASH development by accelerating the breakdown of two lipid biosynthesis enzymes, acetyl-CoA carboxylase 1 (ACC1) and pyruvate carboxylase (PC), in ...

We reported that BMS-303141 administration could decrease the levels of serum lipid and renal lipogenic enzymes acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), HMG-CoA reductase (HMGCR), and ...

Glucose is metabolized to acetyl CoA through the standard glucose metabolic pathway. Acetyl CoA is then carboxylated by acetyl CoA carboxylase (ACC) to form malonyl CoA. This carboxylation step is the ...

The experiment station is the University of Arkansas System Division of Agriculture’s research arm. The breeding work began in 2019 with the discovery of johnsongrass on an Arkansas roadside that ...

Interestingly, acetyl-CoA carboxylase and glycogen phosphorylase were significantly downregulated in patients with lower Lubben Social Network scores, suggesting isolated individuals have lower rates ...

2019). There are currently 74 records of resistance to Italian ryegrass herbicides in the world (HEAP, 2024), five of which are in Brazil, with a highlight to cases of multiple resistance to the ...

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Fibroblast growth factors (FGFs) signal through FGF receptor tyrosine kinases to regulate a wide range of biological processes during development and adulthood. FGF receptors (FGFRs) are involved ...

MANILA, Philippines — The Commission on Audit (COA) has called out the Philippine Atmospheric, Geophysical and Astronomical Services Administration (PAGASA) over P256.07 million worth of ...

Spanish National Research Council (CSIC), Instituto de Ciencia y Tecnología de Alimentos y Nutrición (ICTAN), Jose Antonio Nováis 6 28040, Madrid, Spain ...

The study presents important findings on inositol-requiring enzyme (IRE1α) inhibition on diet-induced obesity (overnutrition) and insulin resistance where IRE1α inhibition enhances thermogenesis and ...